Axonal failure during high frequency stimulation of rat subthalamic nucleus
نویسندگان
چکیده
منابع مشابه
[High frequency stimulation of the subthalamic nucleus in Parkinson's disease].
has been a part of the CNRS unit of Professor Bernard Bioulac in Bordeaux since 2001, prior to which he was 'Chargé de Recherche' (CR1). For his PhD, which he obtained in 1993 in the field of neuroscience and pharmacology, Dr Benazzouz investigated a new therapeutical approach with high-frequency stimulation (HFS) of the subthalamic nucleus in a non-human primate model of Parkinson's disease (P...
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BACKGROUND: Deep-brain stimulation has proven to be beneficial in the treatment of Parkinson’s disease (PD) patients. OBJECTIVE: To investigate the effects of high-frequency stimulation (HFS) to the subthalamic nucleus (STN) on neuronal apoptosis and apoptosis-related gene expression in the substantia nigra pars compacta, and to analyze the neuroprotective effect of HFS-STN. DESIGN, TIME AND SE...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2011
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2011.205807